AKADEMİK ÖZGEÇMİŞ

1. Adı Soyadı : Buket Baddal
2. Unvanı : Doktor (Ph.D.)

4. Yüksek Lisans / Doktora Tezi

4.1. Yüksek Lisans Tez Başlığı ve Tez Danışman(lar)ı:

Evaluation of different methods for detection of Clostridium difficile in faecal specimens from patients suspected of having C. difficile-associated disease. Dr. Mark Wilks, Queen Mary University of London, 2009

4.2 Doktora Tezi Başlığı ve Danışman(lar)ı: Dual RNA-sequencing approach for dissecting non-typeable Haemophilus influenzae and host cell transcriptomes. Dr. Marco Soriani, Prof. Dr. Christoph Tang.  Univesity of Rome Tre, GlaxoSmithKline Vaccines, 2011-2015

5. Doktora Sonrası Bilimsel Araştırma Projesi (Postdoctoral Project): Genome-wide CRISPR/Cas9 screening to identify alternative receptors for streptococcal toxin streptolysin O. Prof. Dr. Michael Wessels, Harvard Medical School, Boston Children’s Hospital, 2015-2018

6. Akademik Unvanlar:

Doçent             Tıbbi Mikrobiyoloji ve Klinik Mikrobiyoloji         Yakın Doğu Üniversitesi     2020-halen

7. Yönetilen Yüksek Lisans ve Doktora Tezleri

7.1 Yüksek Lisans Tezleri

Hameed. D. “Prevalence of Panton-Valentine Leukocidin (PVL) in Methicillin-Resistant Staphylococcus aureus ClinicalIsolates at Near East University Hospital”, Yakın Doğu Üniversitesi Sağlık Bilimleri Enstitüsü, 2020

Potindji TMF. “Investigation of Staphylococcal α-Hemolysin and Exfoliative Toxin A in Methicillin-Resistant Staphylococcus aureus Clinical Isolates”, Yakın Doğu Üniversitesi Sağlık Bilimleri Enstitüsü, 2021

Momani OBA. “Investigation of Staphylococcal Toxic Shock Syndrome Toxin-1 in Methicillin-Resistant Staphylococcus aureus”, Yakın Doğu Üniversitesi Sağlık Bilimleri Enstitüsü, 2021

Akah LM. “Temporal Dynamic of Viral Load in Respiratory Tract Specimens of COVID-19 Patients in Northern Cyprus”, Yakın Doğu Üniversitesi Lisansüstü Eğitim Enstitüsü, 2022

Omowumi BB. “Prevalence of Exfoliative Toxin Genes in Methicillin-Resistant Staphylococcus aureus Clinical Isolates at Near East University”, Yakın Doğu Üniversitesi Lisansüstü Eğitim Enstitüsü, 2022

Ali ASBE. “Investigation of Pseudomonas aeruginosa Biofilm Formation and Toxin Synthesis in Clinical Isolates” Yakın Doğu Üniversitesi Lisansüstü Eğitim Enstitüsü, 2022

Özler B. “Evaluation of Biofilm Formation and Detection of Exopolysaccharide Encoding Genes Among Pseudomonas aeruginosa Clinical Isolates At Near East University Hospital”, Yakın Doğu Üniversitesi Lisansüstü Eğitim Enstitüsü, 2023

7.2 Doktora Tezleri

Amro MMY. “Hypervirulence phenotypes of Klebsiella pneumoniae circulating in the healthcare system in Northern Cyprus”, Yakın Doğu Üniversitesi Lisansüstü Eğitim Enstitüsü, 2022-halen

8. Yayınlar

8.1 Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI, AHCI, ESCI, Scopus)

Ali ASBE, Ozler B, Baddal B. Characterization of Virulence Genes Associated with Type III Secretion System and Biofilm Formation in Pseudomonas aeruginosa Clinical Isolates. Curr Microbiol. 2023; 80, 389

Baddal B, Oktay MN, Bostanci A. Yenen MC. Prevalence and genotype screening of human papillomavirus among women attending a private hospital in Northern Cyprus: an 11-year retrospective study. BMC Women's Health. 2023; 23, 297

Lajunen TJ, Sullman MJM, Baddal B, Tekes B, Apostolou M. Antibiotic Knowledge, Attitudes and Behaviours among the Population Living in Greece and Turkey. Antibiotics 2023; 12, 1279.

Sullman MJM, Lajunen TJ, Baddal B, Apostolou M. Antibiotics Knowledge, Attitıdes and Behaviors among the Population Living in Cyprus. Antibiotics. 2023; 5, 897.

Baddal B, TM Lajunen, MJM Sullman. Knowledge, attitudes and behaviours regarding antibiotics use among Cypriot university students: a multi-disciplinary survey. BMC Med Educ. 2022; 22, 847.

TMF Potindji, OAA Momani, BB Omowumi, Baddal B. Screening of Toxin Genes in Methicillin-Resistant Staphylococcus aureus Clinical Isolates from a Hospital Setting in a Tertiary Hospital in Northern Cyprus. Pol. J. Microbiol. 2022; 71(4):491-497.

Bostanci A, Baddal B. The impact of COVID-19 on the molecular epidemiology of seasonal viral respiratory infections, Cyprus. J of Infection. 2022, Vol 84, Issue 6, E105-E107.

Tuncel G, Ergoren MC, Baddal B, Tulay, P Ozverel CS, Guler E, Suer HK, Sayan M., Sanlidag T. Detection of SARS-CoV-2 N501Y mutation among SARS-CoV-2 variants of concern circulating in Northern Cyprus. Future Virology. 2022; 17,8.

Baddal B., Uzun Ozsahin D., Uzun B., Sanlidag T. Evaluation of the Effectiveness of Double Border-Screening Strategy with and without Quarantine in the Prevention of COVID-19. IEEE. 2022 Advances in Science and Engineering Technology International Conferences (ASET). 2022; Pages 1-4.

Baddal B. Emerging Technologies in Infectious Disease Treatment, Prevention and Control. Frontiers in Cellular and Infection Microbiology, 1831.

E Özbilge, T Sanlidag, E Ozbilge, B Baddal. Artificial Intelligence-Assisted RT-PCR Detection Model for Rapid and Reliable Diagnosis of COVID-19. MDPI Applied Sciences. 2022; 12(19), 9908.

Andac G., Kalender A., Baddal B., Basmaci F. Impact of Different Access Cavity Designs and Ni-Ti Files on the Elimination of Enterococcus faecalis from the Root Canal System. MDPI Applied Sciences. 2022; 12(4), 2049.

Baddal B, Sanlidag T, Uzun B, Ozsahin DU. The use of double border-screening strategy in the surveillance and prevention of COVID-19. Journal of Infection and Public Health. 2021; 14, Issue 6, Pages 757-758.

Baddal B, Bostanci A, Suer K, Sanlidag T. SARS-CoV-2 was already in circulation in Northern Cyprus in the prepandemic period. The Journal of Infection. 2021; 83(2): e25–e26.

Baddal B, Marrazzo P. Refining Host-Pathogen Interactions: Organ-on-Chip Side of the Coin. Pathogens. 2021; 10 (2), 203.

Amin DH., Guler E, Baddal B. Prevalence of Panton-Valentine leukocidin in methicillin-resistant Staphylococcus aureusclinical isolates at a university hospital in Northern Cyprus: a pilot study. BMC Research Notes.2020; 13(1):490.

Teralı K, Baddal B, Gülcan HO. Prioritizing potential ACE2 inhibitors in the COVID-19 pandemic: Insights from a molecular mechanics-assisted structure-based virtual screening experiment. Journal of Molecular Graphics and Modelling.2020; Volume 100, November 2020, 107697.

Baddal B. and Cakir N. Co-infection of MERS-CoV and SARS-CoV-2 in the same host: a silent threat. Journal of Infection and Public Health. 2020;13(9): 1251–1252.

Sultanoglu N., Baddal B., Suer K., Sanlidag T. Current situation of COVID-19 in Northern Cyprus. Eastern Mediterranean Health Journal. 2020; 26, 6.

Baddal B. Characterization of biofilm formation and induction of apoptotic DNA fragmentation by nontypeable Haemophilus influenzae on polarized human airway epithelial cells. Microb Pathog. 2020; 141 (2020) 103985.

Çırakoğlu S, Baddal B, İslam A. The Effectiveness of Laser-Activated Irrigation on the Apical Microleakage Qualities of MTA Repair HP and NeoMTA Plus in Simulated Immature Teeth: A Comparative Study. Materials 13.2020; (15), 3287

Baddal B. Next-generation technologies for studying host-pathogen interactions: a focus on dual transcriptomics, CRISPR/Cas9 screening and organs-on-chips Pathog Dis. 2019; 77 (6) ftz060.

Pinho-Ribeiro FA, Baddal B, Haarsma R, O’Seaghdha M, Yang NJ, Blake KJ, Portley M, Verri WA, Dale JB, Wessels MR, Chiu IM. Blocking Neuronal Signaling to Immune Cells Treats Streptococcal Invasive Infection. Cell. 2018; 173(5):1083-1097

Velarde J, O'Seaghdha M, Baddal B, Bastiat-Sempe B, Wessels MR. Binding of NAD+-glycohydrolase to streptolysin O stabilizes both toxins and promotes virulence of group A Streptococcus. mBio. 2017; 8(5):e01382-17

Baddal B, Muzzi A, Censini S, Calogero RA, Torricelli G, Guidotti S, Taddei AR, Covacci A, Pizza M, Rappuoli R., Soriani M, Pezzicoli A. Dual RNA-seq of non-typeable Haemophilus influenzae and host cell transcriptomes reveals novel insights into host-pathogen cross talk. mBio. 2015; 6(6):e01765-15

Ercoli G, Baddal B, Greco A, Marchi S, Petracca R, Arico B, Pizza M, Soriani M. Development of a  serological assay to predict antibody bactericidal activity against non-typeable Haemophilus                      influenzae. BMC Microbiol. 2015; 15:87

Martin K, Baddal B, Mustafa N, Perry C, Underwood A, Constantidou C, Loman N, Kenna DT, Turton JF. Clusters of genetically similar isolates of Pseudomonas aeruginosa from multiple hospitals in the UK.         J Med Microbiol. 2013; 62(Pt 7):988-1000

Turton JF, Baddal B and Perry C. Use of the accessory genome for characterization and typing of  Acinetobacter baumannii. J Clin Microbiol. 2011; 49(4):1260-6

Wong V, Levi K, Baddal B, Turton JF, Boswell TC. Spread of Pseudomonas fluorescens due to  contaminated drinking water in a bone marrow transplant unit. J Clin Microbiol. 2011; 49(6): 2093–2096

8.2 Ulusal hakemli dergilerde yayımlanan makaleler

Baddal B, Bostanci A, Aksoy T, Kucukciloglu Y, Suer K. A Rare Case of Rickettsia and Herpes Simplex Virus 1 Co-infection in a Male Patient with Meningoencephalitis. 2023 (in press)

Baddal B, Bostanci A., Suer K. Two Cases of Varicella Zoster Virus Meningitis without Fever and Rash: Na Unexpected Clinical Presentation, J Biotechnol and Strategic Health Res. 2023;7(3):220-225

Güler E, Taner F, Şanlıdağ E, Tülay P, Çerkez Ergören M, Baddal B, Özverel C S, Tuncel G, Süer K, Şanlıdağ T. Comparison of the Rapid Antigen Test to RT-qPCR in Diagnosis of SARS-CoV-2: A University Experience in Northern Cyprus. Clin Exp Health Sci 2023; 13: 525-529.

Baddal B, Bostanci A, Suer K. HSV-2 Associated Meningitis Case: A Challenging Diagnosis in An Immunocompetent Woman. Journal of Emergency Medicine Case Reports. 2023;14(3): 60-62

MMY Amro, Baddal B, K Suer, N Demir. A case of community-acquired pneumococcal meningitis following acute sinusitis and unseccessful former antimicrobial therapy. Journal of Biotechnology and Strategic Health Research. 2023;7(1), 75-80

Baddal B, Bostanci A., Evren EU, Gazi U. Assessment of Respiratory Viral Co-infections Among SARS-CoV-2-Infected Patients. FLORA The Journal of Infectious Diseases and Clinical Microbiology. 2023;28(2):217-224

D Kaynarca, T Korkmazhan, MN Oktay, T Sanlidag, Baddal B. Monitoring of SARS-CoV-2 RNA in public areas: An investigation of environmental surface contamination. 203-206

Baddal B. Microfluidic organ-chips and infectious diseases: insights from the development and applications perspective. Cyprus J Med Sci. 2022;7(1):1-8.

Ozverel CS, Tulay P, Ergoren MC, Guler G, Baddal B, Suer K, Sanlidag T. SARS-CoV-2 Alpha Variant Infection of a Patient Immunized by Inactive Sinovac (CoronaVAc) Vaccine. The EuroBiotech Journal. 2022. Volume 6, Issue 1.

Güler E, Özbilgin A, Çavuş I, Baddal B, Etikan I, Başer KHC, Şanlıdağ T. In vitro Anti-Leishmanial Activity of Essential Oils Extracted from Plants Growing in Northern Cyprus Against Leishmania tropica. Türkiye Parazitolojii Dergisi. 2021. 45 (2), 101

Tuncel G, Ergoren MC, Baddal B, Tulay P, Arikan A, Guler E, Ozverel CS, Suer HK, Sayan M, Taer Sanlidag T. Comparison of RT-qPCR results of different gene targets for SARS-CoV-2 in asymptomatic individuals during COVID-19 pandemic. The EuroBiotech Journal.2021.

Baddal B, Guler E, Suer E. Antibiotic Resistance in Pseudomonas aeruginosa Isolated from Hospital and Community-Acquired Infections: Current Status in Northern Cyprus. Klimik Dergisi. 2021. 34 (1), 31-6

Yilmaz AB, Guler E, Baddal B. Knowledge, perception and implementation of personal protective measures by citizens during the COVID-19 outbreak in Northern Cyprus: a cross-sectional survey. Cyprus J Med Sci. 2021; 6(3): 208-216.

Baddal B. Importation and Transmission Routes of COVID-19 into Northern Cyprus: Considerations and Challenges. Erciyes Med J. 2020; 42(3): 00–00.

Güler E, Süer HK, Güvenir M, Baddal B, Dalkan C. Investigation of the prevalence of group A beta haemolytic streptococcus and efficiency of streptococcus rapid antigen test in patients prediagnosed with acute tonsillopharyngitis in a university hospital. Mediterr J Infect Microb Antimicrob. 2019; 8:38.

Güler E, Baddal B, Güvenir M, Süer HK. Epidemiological surveillance of rotavirus and adenovirus among patients with acute gastroenteritis: a single center experience in North Cyprus. Cyprus J Med Sci. 2019; 4: 229-234.

8.3 Yazılan uluslararası kitaplar veya kitap bölümleri

 Kitap bölümü

Baddal. B., “Tek nükleotit polimorfizm [Single nucleotide polymorphism (SNP)] ve tek lokus tiplendirme yöntemleri: prensipleri, metodoloji ve kullanım alanları” Moleküler Mikrobiyoloji: Tanı ve Epidemiyoloji. Akademisyen Yayınevi, 2022

8.4 Sözlü Bildiriler

 Baddal B, Bostancı A, Özbilge E. Makine öğrenimi destekli hızlı servikal insan papilloma virüs genotiplendirme. 7. Ulusal Klinik Mikrobiyoloji Kongresi. Kasım 2023, Bodrum, Türkiye 

Baddal B, Oktay MN, Bostancı A, Yenen MC. Kuzey Kıbrıs’ta özel bir hastaneye başvuran kadın hastalarda human papilloma virus (HPV) genotiplendirme: 11 yıllık retrospektif çalışma. 38. ANKEM Akılcı Antibiyotik Kullanımı Kongresi, Haziran 2023, Girne, KKTC

 Baddal B, Akan G, Tuncel G, Kalaycı M, Bostancı A, Şanlıdağ T. Pandemi sonrası tripledemi (üçlü salgın) ile mücadele: COVID-19, influenza ve RSV multipleks RT-qPCR Tanı Kiti Geliştirilmesi. 38. ANKEM Akılcı Antibiyotik Kullanımı Kongresi, Haziran 2023, Girne, KKTC

Ali A, Baddal B. Pseudomonas aeruginosa klinik suşlarında tip 3 sekresyon sistemi (T3SS)’nin araştırılması. 38. ANKEM Akılcı Antibiyotik Kullanımı Kongresi, Haziran 2023, Girne, KKTC

Baddal B. İnfeksiyon Hastalıklarını Önlemede Yapay Zeka Kullanımı. Hastane İnfeksiyonları Kongresi 2022, Kasım2022, Antalya, Türkiye

Baddal B. Organ çipler ve enfeksiyon hastalıklarında kullanım alanları. XL. Uluslararası Türk Mikrobiyoloji Kongresi,Kasım 2022, Antalya, Türkiye

Baddal B. COVID-19 RT-qPCR Tanısını Yapay Zeka Kullanarak Hızlandırabilir miyiz? TMC Yapay Zeka Sempozyumu, Haziran 2022 (Çevrim İçi) 

Baddal B., Sanlidag T., Ozbilge E. Use of artificial intelligence on rapid COVID-19 diagnosis using real-time polymerase chain reaction data. European Congress of Clinical Microbiology & Infectious Diseases, Nisan 2022, Lisbon, Portekiz

Baddal B., Ozsahin DU, Uzun B., Sanlidag T. Evaluation of the Effectiveness of Double Border-Screening Strategy with and without Quarantine in the Prevention of COVID-19. Advances in Science and Engineering Technology (ASET), Subat 2022, Dubai, BAE

Baddal B., Bostanci A. Gazi U. Respiratory viral co-infections among SARS-CoV-2 cases in Northern Cyprus. European Biotechnology Congress 2021, Eylül 2021 (Çevrim İçi) 

Baddal B. K.K.T.C.’de COVID-19 deneyimi: ilk vakadan günümüze. TMC Çevrim İçi Mikrobiyoloji Sempozyumu, Aralık 2020

Baddal B. Genome-wide CRISPR-Cas9 screening to identify alternative receptors for streptococcal toxin streptolysin O. European Congress of Clinical Microbiology & Infectious Diseases, Nisan 2019, Amsterdam, Hollanda

Baddal. B. Tiplendirilemeyen Haemophilus influenzae izolatlarında biyofilm olusumunun insan hava yolu epitel hücreleri üzerinde araştırılması, 5. Ulusal Klinik Mikrobiyoloji Kongresi, Ekim 2019, İzmir, Türkiye

Baddal B, Wessels MR. Genome-Wide CRISPR/Cas9 Screening to Identify Alternative Receptors for Streptococcal Toxin Streptolysin O. American Society of Microbiology (ASM) Microbe, Haziran 2019, San Francisco, ABD

Baddal B., Wessels MR. Genome-wide CRISPR/Cas9 screening to identify alternative receptors for streptolysin O. Uluslararası 10. Moleküler ve Tanısal Mikrobiyoloji Kongresi. Kasım 2018, Antalya, Türkiye

 Baddal B, Tian S, Dong M, Wessels MR. Genome-wide CRISPR/Cas9 screening to identify alternative receptors for streptolysin O. 20th Lancefield International Symposium on Streptococci and                Streptococcal Diseases. Ekim 2017, Fiji, Nadi

 Baddal B. Dual RNA-seq sequencing approach for dissecting host-pathogen transcript transcriptome    during non-typeable Haemophilus influenzae colonization of human bronchial epithelial cells.                  European Initiative of Microbiology and Infectious Diseases Symposium. Ekim 2014, Berlin, Almanya

Baddal B. Deep sequencing approach for dissecting host-pathogen transcript transcriptome during non-non-typeable Haemophilus influenzae colonization of human bronchial epithelial cells.                         Society of General Microbiology Annual Conference. Nisan 2014, Liverpool, İngiltere

9. Patentler

“Advanced Pulmonary Models” U.S. PCT Patent Application. EMULATE-19008, 9 Mayıs 2018

“Advanced Pulmonary Models” U.S. PCT Patent Application. EMULATE-18992, 23 Mayıs 2018

“Antagonism of CGRP and Its Receptor Signaling to Treat Bacterial Infections” U.S. Provisional Patent Appl. 62/662,457, 25 Nisan 2018

“Methods of Treatment of Bacterial Infections and Pain Associated Therewith” U.S. Provisional Patent Appl. 62/521,776, 19 Haziran 2017

10. Bilimsel ve Mesleki Kuruluşlara Üyelikler

TMC-KKTC Mikrobiyoloji Platformu – Başkan                                                      2019’dan beri

Türk Mikrobiyoloji Cemiyeti                                                                               2018’den beri

European Society of Clinical Microbiology and Infectious Diseases                        2017’den beri

American Society for Microbiology                                                                     2014’den beri

Kıbrıs Türk Biyologlar Doğayı Araştırma ve Koruma Derneği                                 2011’den beri

11.Ödüller

ANKEM Akılcı Antibiyotik Kullanımı Kongresi, Sözlü Bildiri Birincilik Ödülü (2023)

Yakın Doğu Üniversitesi, Yayın Ödülü (2022)

6.Erciyes Tıp Tıbbi Genetik Kongresi, Sözlü Bildiri Ödülü (2021)

Yakın Doğu Üniversitesi, Yayın Ödülü (2021)

Yakın Doğu Üniversitesi, Genç Araştırmacı Ödülü (2020)

European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) Travel Grant (2019)

XXXVIII. Türk Mikrobiyoloji Kongresi, Federation of European Microbiological Societies (FEMS) Kayıt ve Konaklama Bursu (2018)

Lancefield Symposium on Streptococci and Streptococcal Diseases, Genç Araştırmacı Ödülü (2017)
Report of Invention (ROI) Use of Botulinum Neurotoxins (BoNTs) to Treat or Prevent Necrotizing Fasciitis and Bacterial Infections (2017)         

European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Attendance and Travel Grant (2017)         

Marie Skłodowska-Curie Actions, the 7th Framework Program, 3-year PhD Fellowship Grant, EIMID-ITN Network (2011)