ACADEMIC CURRICULUM VITAE
1. Name Surname: Burak Durmaz
2. Title: Doctor (Ph.D.)
3. Education:
Degree Department/Program University Year
Bachelor's Degree Biology Education Dokuz Eylül University 2009-2024
Master's Degree Medical Biochemistry Ege University Faculty of Medicine 2017-2018
Ph.D. Medical Biochemistry Ege University Faculty of Medicine 2018-2024
4. Master's / Ph.D. Thesis
4.1. Master's Thesis Title and Advisor(s):
"Antioxidant Activity and Induction of Apoptosis of Hydroxycinnamic Acids Found in Blueberry on Cancer Cell Culture" - Advisor: Prof. Dr. Eser Yıldırım Sözmen
4.2. Ph.D. Thesis / Medical Specialty Thesis Title and Advisor(s):
"Purification of Diamine Oxidase (DAO) from Natural Sources and Production of Enzyme-Enriched Foods" - Advisor: Prof. Dr. Eser Yıldırım Sözmen
5.Work Experience
1) Yedikule Chest Diseases and Chest Surgery Training and Research Hospital - Biochemistry Laboratory - 2009
2) Yedikule Chest Diseases and Chest Surgery Training and Research Hospital - Microbiology Laboratory - 2010
3) Intern Teacher at DMO High School and Şirinyer Anatolian High School - 2013/2014
4) Measurement methods of DAO enzyme activity, analysis with UHPLC method - University of Barcelona - 01.03.2023-01.05.2023
5) Assistant Professor - Department of Medical Biochemistry, Faculty of Medicine, Near East University - 01.02.2024
TECHNIQUES USED
Cell Culture Techniques, Lysosomal Storage Diseases Techniques, Enzyme and Microorganism Immobilization Techniques, Protein Purification, Elisa Techniques, Antibiotic Production with Microorganisms, Chromatography Techniques, Biotechnology Techniques, Natural Products and Cosmetic Studies, Plant Extraction, Spectrophotometer, Elisa, HPLC, LC-MS / MS.
6. Publications
6.1. Articles Published in International Peer-Reviewed Journals (SCI, SSCI, AHCI, ESCI, Scopus)
1) Durmaz, B., Oktay, L. M., Mehmedov, H., Günel, N. S., Yıldırım, H. K., & Sözmen, E. Y. (2018, December). Hydroxycinnamic Acids in Wild Blueberry and Effects of Hydroxycinnamic Acids on Apoptosis Induction in Cancer Cell Culture. In Proceedings (Vol. 2, No. 25, p. 1528). MDPI. https://doi.org/10.3390/proceedings2251528
2) Hikmet M., Latife M.O., Burak Durmaz, Nur Selvi Günel, Hatice Kalkan Yıldırım, Eser Yıldırım Sözmen, “Propolis Prevents İnhibition of Apoptosis by Potassium Bromate in CCD 841 Human Colon Cell”, Cell Biochem Funct. 2020 Jun;38(4):510-519- DOI: 10.1002/Cbf.3475
3) Özgönül, A. M., Aşık, A., Durmaz, B., Aslaminabad, R., Gündüz, C., & Sozmen, E. Y. (2020). “Antiproliferative Effect Of Rosehip Tea Phenolics İn Prostate Cancer Cell Lines.” Turkish Journal Of Biochemistry, 1. https://doi.org/10.1515/tjb-2019-0262
4) Çelik, K., Bilim, P., Garip, G., Durmaz, B., SÖZMEN, E. Y., & Meral, B. A. K. A. (2021). Prenatal Stress İmpairs Recognition Memory And Leads To Neurodevelopmental Deficits İn Hippocampus Of Adolescent Rats With Early Acute Pentylenetetrazole-Kindling. The European Research Journal. https://doi.org/10.18621/eurj.801699
5) Çelik, K., Bilim, P., Garip, G., Durmaz, B., SÖZMEN, E. Y., & Meral, B. A. K. A. “Acute hypoxia exposure following prenatal stress impairs hippocampus and novelty-seeking behavior in adolescent rats, International journal of developmental neuroscience”.Int J Dev Neurosci. 2022 Feb;82(1):85-95 DOI: 10.1002/jdn.10162
6) Hatice Ozisik, Ayse Çekin, Aslı Suner, Burak Durmaz, Buket Ozel, Nur Selvi Gunel, Gokhan Ozgen, Mehmet Erdogan. “Evaluation of IL-10, MCP-1, IFN Gamma, And Protectin D1 Levels İn Patients With Hashimoto’s Thyroiditis.” Ir J Med Sci. 2023 Feb; 192(1): 177-184. https://doi.org/10.1007/s11845-022-03231-3
7) Burak Durmaz, Latife Merve Oktay, Hikmet Memmedov, Nur Selvi Gunel, Hatice Kalkan Yildirim, Eser Yildirim Sozmen (2023) “Solvation Methods Affect the Amount of
Active Components in the Extract of Propolis as well as Its Anti-Inflammatory Activity in THP-1 Cells” European Journal of Biology DOI: 10.26650/EurJBiol.2023.1247199
8) Çopur, O., Yazıcı, H., Canbay, E., Durmaz, B., Canda, E., Ucar, S. K., Coker M., Sozmen, E. Y. (2024). Glycosaminoglycan-induced proinflammatory cytokine levels as disease marker in mucopolysaccharidosis. Cytokine, 173, 156410. https://doi.org/10.1016/j.cyto.2023.156410
9) Unal Kocabas G, Yildirim Simsir I, Sarer Yurekli B, Durmaz B et al. The association of plasma pancreastatin levels with insulin resistance in patients with gestational diabetes mellitus. Obstetric Medicine. 2023;0(0). doi:10.1177/1753495X231216032
6.2. Papers Presented at International Scientific Meetings and Printed in the Proceedings Book
1) Hikmet Memmedov, Latife Merve Oktay, Burak Durmaz, Nur Selvi Günel, Hatice Kalkan Yıldırım, Eser Yıldırım Sözmen, “Antı-Angiogenic Effect of Propolis is Closely Related To The Solvation Method and Biotransformatıon Process”, Turkish Journal Of Biochemistry, 22-24 September 2019.
2) B. Durmaz, H. Kalkan Yildirim, N. Selvi Günel, Latife Oktay, Hikmet Memmedov, and E. Sözmen, “Hydroxycinnamic Acids in Wild Blueberry and Effects of Hydroxycinnamic Acids on Apoptosis,” presented at the 2nd cell death congress, 2018.
3) B. Durmaz, E. Dündar, E. Canbay, H. Memmedov, H. Kalkan Yildirim, and E. Sözmen, “Effect of Different Extraction Techniques on Anti-inflammatory Activity of Propolis” presented at the International Biochemical congress, 2017.
4) Hikmet Memmedov, Hatice Kalkan Yıldırım, Latife Oktay, Burak Durmaz, Nur Selvi Günel, Ezgi Dündar, Eser Sözmen, “Farklı Çözgenlerde Hazırlanmış Propolisin Sağlıklı ve Kanser Hücre Hatları Üzerindeki Sitotoksik Etkisi,” presented at the International Congress of Agriculture, Environment and Health (ICAEH), 2018.
5) H. Kalkan Yildirim, E. Dündar, B. Durmaz, N. Selvi Günel, Hikmet Memmedov, and E. Sözmen, “Allergenic Phenolic Content and Antioxidant Capacity of Biotransformed Propolis by Lactobacillus plantarum,” presented at the 6th International Muğla Beekeeping Pine Honey Congress, 2018.
6) L. M. Oktay, B. Durmaz, H. Memmedov, H. Kalkan Yildirim, N. Selvi Günel, ve E. Sözmen, “Biyolojik olarak transforme edilen propolis örneklerinin HCT-116 kolon kanseri hücrelerinde sitotoksik etkisi”-4. Ege Hematoloji Onkoloji Kongresi, İzmir, 2018.
7) Hikmet Memmedov, B. Durmaz, Latife Oktay, N. Selvi Günel, H. Kalkan Yıldırım, and E. Sözmen, “Biologically transformed Propolis Exhibits Cytotoxic Effect on A375 Malignant Melanoma Cells In Vitro,” presented at the 2nd International Conference on Natural Products for Cancer Prevention and Therapy, 2017.
8) N. Selvi Günel, L. M. Oktay, H. Memmedov, B. Durmaz, H. Kalkan Yıldırım, E. Yıldırım Sözmen “Cytotoxic Effect of Biologically Transformed Propolis on HCT-116 Human Colon Cancer Cells” Conference Proceedings, Amsterdam The Netherlands Feb 07-08,2019.
9) Burak Durmaz, Latife Merve Oktay, Hikmet Memmedov, Nur Selvi Günel, Hatice Kalkan Yıldırım, Eser Yıldırım Sözmen “Induction of APAF-1 and TRAİL by Bilberry Tea in HCT-116 Colon Cancer Cell Line”- 27th Balkan Clinical Laboratory Federation (BCLF) And The 30th National Tbs-October-27-31, 2019 in Antalya, Turkey. Tam Metin Bildiri
10) Burak Durmaz, Latife Merve Oktay, Hikmet Memmedov, Nur Selvi Günel,Hatice, Kalkan Yıldırım ,Eser Yıldırım Sözmen; “Propolisin Thp-1 Hücre Hattındaki İnflamatuvar Etkisi Üzerine Biyotransfromasyon ve Ekstaksiyon Yöntemlerinin Etkisi/Effect Of Biotransformation And Extraction Methods on the Anti-inflammatory Effect of Propolis in THP-1 Cell-Line”- İnflamasyon Temalı VII Türkiye in Vitro Diagnostik (IVD) Sempozyumu-27-29 Nisan 2022-Online
11) Burak Durmaz, Erhan Canbay, Şura Öztürk Baykan, Hatice Kalkan Yıldırım, Eser Yıldırım Sözmen “Gıdalarda Histamin Miktarının Düşürülmesi İçin Yenilikçi Bir Uygulama: Diamin Oksidaz ile Zenginleştirme”-33.Ulusal Biyokimya Kongresi/Uluslararası Biyokimya Kongresi-26-30 Ekim 2022-Çeşme/İZMİR
6.3. National/International Books or Book Chapters Written
1) Advanced Mitochondrial Medicine - Role of Mitochondria and Reactive Oxygen Species in Physiology and Pathology-Chapter 5-Translation-2020
2) Febs Advanced 2022 Lecture Course-3600 Lysosome: from structure to genomics, from function to disease-Course Book-Celsus Information Technologies San.Tic.L.T.D.Ş.-2022-ISBN: 978-605-71083-7-1
6.4. Articles Published in National Peer-Reviewed Journals
Öztürk, Ş., Durmaz, B., Memmedov, H., Oktay, L. M., Günel, S. N., Olukman, M., & Sözmen, E. Y. (2021) “The Effect of Ferulic Acid on Cytokine Release in Lipopolysaccharide-Induced Human Leukemia Monocytic Cells.” Ege Medical Journal, 60(1), 39-50. https://doi.org/10.19161/etd.887360
7. Administrative Duties
2012-2014 Dokuz Eylül University Department of Science and Mathematics Student Representative
2021- Ege University Department of Medical Biochemistry Student Representative and Quality Ambassador
8. Memberships in Scientific and Professional Organizations
Turkish Biochemistry Association
EFLM Academic
IFCC-Academic
MOKAD
9. Awards
1) 2018-2022 YÖK 100/2000 Doctoral Scholarship- "NATURAL PRODUCTS AND COSMETICS"
2) 2019/3 Event Participation Scholarship-TÜBİTAK-2019
3) 2020/1 2211-A General Domestic Doctoral Scholarship-TÜBİTAK
4) Full scholarship for participation in the 25th IFCC-EFLM European Congress of Clinical and Laboratory Medicine - Rome (IT), May 21-25, 2023
5) Full scholarship to the (YSF 2023) at the 47th FEBS Congress-Tours, France, 6–8 July 2023.
10. Undergraduate and Graduate Courses Given in the Last Two Years
Ege University Faculty of Medicine-1st-year students
COURSE
Introduction to solution preparation - introduction to laboratory applications (PRACTICAL)
Amino acids (PRACTICAL)
Proteins (PRACTICAL)
Spectrophotometer (PRACTICAL)
Carbohydrates I – II (PRACTICAL)
Lipids (PRACTICAL)
DNA cleavage and electrophoresis (PRACTICAL)
Enzymes (PRACTICAL)
Physical and chemical properties of urine (PRACTICAL)
Bilirubin (PRACTICAL)
Ketone bodies (PRACTICAL)
